Hydrogen Peroxide as a Damage Signal in Tissue Injury and Inflammation: Murderer, Mediator, or Messenger?
نویسندگان
چکیده
منابع مشابه
Hydrogen Peroxide in Inflammation: Messenger, Guide, and Assassin
Starting as a model for developmental genetics, embryology, and organogenesis, the zebrafish has become increasingly popular as a model organism for numerous areas of biology and biomedicine over the last decades. Within haematology, this includes studies on blood cell development and function and the intricate regulatory mechanisms within vertebrate immunity. Here, we review recent studies on ...
متن کاملHydrogen peroxide: a signaling messenger.
Hydrogen peroxide (H2O2) is a well-documented component of living cells. It plays important roles in host defense and oxidative biosynthetic reactions. In addition there is growing evidence that at low levels, H2O2 also functions as a signaling agent, particularly in higher organisms. This review evaluates the evidence that H2O2 functions as a signaling agent in higher organisms in light of the...
متن کاملHydrogen peroxide Acts as a Secondary Messenger for Production of Silymarin in Ag+ Elicited Silybum marianum Hairy Root Cultures
This study was performed to investigate the effect of Ag+ as an elicitor on the activity of antioxidant enzymes, content of H2O2, accumulation of total tocopherol and antioxidant activity in hairy root cultures of Silybum marianum (L.) Gaertn. The hairy roots were treated with 2 mM Ag+. The treated and non-treated hairy roots were harvested in the same time and data on H2O2 content, DPPH, tocop...
متن کاملHydrogen peroxide functions as a stress signal in plants
Plants have evolved complex regulatory mechanisms in adapting to various environmental stresses. One of the consequences of many stresses is an increase in the cellular concentration of reactive oxygen species (ROS), which are subsequently converted to hydrogen peroxide (H 2 O 2 ). An oxidative burst caused by biotic or abiotic stress leads to a disturbance in the cellular redox balance and is ...
متن کاملHydrogen peroxide as a signal controlling plant programmed cell death
Hydrogen peroxide (H2O2) has established itself as a key player in stress and programmed cell death responses, but little is known about the signaling pathways leading from H2O2 to programmed cell death in plants. Recently, identification of key regulatory mutants and near-full genome coverage microarray analysis of H2O2-induced cell death have begun to unravel the complexity of the H2O2 networ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cellular Biochemistry
سال: 2014
ISSN: 0730-2312
DOI: 10.1002/jcb.24683